Jed and Jethro are talking about a “fast” girl Jethro knew back in the hills:
Jethro: Uncle Jed, she handed me a big old sugar cookie, looked at me and said, “Jehtro, if you had a choice between that cookie and me, which one would you take“. Uncle Jed, that’s when I found out just how fast she was!
(Jed leans in close to hear the rest of the sordid story.)
Jethro: I had to run nearly a mile to get away from her with that cookie!
Jed Clampett: (shaking his head) Jethro, some day me and you got to have a long talk.